MONROVIA – The Case Management Pillar, spearheaded by the Ministry of Health on the Mpox Response, has announced four (4) deaths reportedly associated with Mpox and other infections or conditions – at the Starbase Isolation facility in Monrovia, and the Liberian Government Hospital in Buchana, respectively. Three (3) of the patients died at the Star Base treatment facility in Monrovia, while one (1) died at the Liberian Government Hospital in Buchana, Grand Bassa County. The Mpox National IMS is investigating.
According to a press release issued on Monday, September 29, 2025, by NPHIL Director-General Dr. Dougbeh Chris Nyan, hospital reports indicated that some of the deceased patients also had other infections or conditions such as HIV/AIDS and sepsis in addition to Mpox, and were receiving treatment at different times. These are the first deaths reported in Liberia since the outbreak was announced by the Africa Centers for Disease Control and Prevention (Africa-CDC) and the WHO a year ago in August 2024. For further molecular analysis and investigation, the National Reference Laboratory at the National Public Health Institute of Liberia (NPHIL) will conduct genomic sequencing on the specimens of the reported deceased cases.
In recent times in the wake of the upsurge of cases in the West African sub-region and the country, Liberia’s public health surveillance and response system have remained on heightened alert. NPHIL continues to strengthen cross-border surveillance, increase active case search, and strengthen diagnostics in order to break the human-to-human transmission in the communities. Also, the IMS is encouraging the improvement of Case Management at the hospitals and isolation center so as to increase prognosis and prevent any deaths that may be associated with Mpox. Mpox is a self-limited disease caused by the Monkeypox virus, but can be severe.
To date, with the reported 4 associated fatalities by the Case Management Pillar, Liberia’s Mpox status stands at 923 laboratory confirmed cases, 169 total active cases, and 750 total recovered cases as of September 29, 2025. Meanwhile, the population is advised to remain calm with no panic, follow all public health sanitary regulations such as frequent handwashing, avoiding contact with suspected persons, and report suspected cases to health facilities or call the Emergency Number 4455.
